Weight Loss - Saxenda
What is Saxenda?
Saxenda is a prescription only, once daily injection that is used to promote weight loss in patients who are either obese or who are overweight (with a Body Mass Index of 28 or more) and have additional health risk factors. It contains the active ingredient liraglutide, which was originally developed to treat diabetes. Saxenda has been available as a licensed medicine for weight loss since 2014.
Saxenda works in the same way as natural substance found in the body called GLP-1, which helps to regulate blood sugar after eating. This decreases the production of glucagon, a hormone that opposes insulin and slows down the emptying of the stomach. This in turn lowers hunger and increases feelings of fullness.
How to take Saxenda
Saxenda is given via sub-cutaneous injection once a day using a pen and patients follow a progressive, four week dose escalation schedule which is designed to minimise any potential gastrointestinal symptoms. Patients need one five pen pack to complete the dose escalation. Thereafter, one pack equates to a one-month treatment at the 3.0mg dose (the maintenance dose).
Using the prefilled pen is very easy, it is designed to be injected on the abdomen, front of the thighs or upper arm sub-cutaneously and is administered just once a day.
Saxenda has been tested for the promotion of weight loss in several clinical trials. The SCALE Obesity and Pre-Diabetes phase 3a trial showed that the 3,731 participants lost an average of 8 per cent of their body weight over a 56 week trial. In evidence presented to The American Society for Metabolic and Bariatic Surgery, the same study showed that 92 per cent of patients lost weight, when 3mg liraglutide was used in conjunction with diet and exercise modifications.
Common side effects with Saxenda include nausea, vomiting, diarrhea and constipation, although these usually lessen over time and not everybody experiences them. It is important to stay well hydrated while taking Saxenda. Other potential side effects include low blood sugar, headache, indigestion, abdominal discomfort, constipation, decreased appetite, dizziness, fatigue, fever, toothache and injection site reactions. Rare side effects may include pancreatitis and thyroid events.
Watch how Saxenda works in the body
Click here for the video.
ECG is an accredited training provider, offering a wide range of face to face and online training to the NHS, community pharmacy, private healthcare clients and aesthetic practitioners. EGC courses are designed and delivered by experienced healthcare professionals to support practitioner’s clinical training needs.
ECG provides a fully funded two hour webinar session aimed at setting up a weight management service or include one to their current facility. To be eligible for insurance on Saxenda it is mandatory to take ECG training.
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